Purpura trombocitopenica hematologia pdf

Primary immune thrombocytopenia itp is an acquired immunemediated disorder characterized by isolated low platelet count and the absence of any other cause of the thrombocytopenia. Moschcowitz was the first to inform multiple hyaline thrombi as the primordial finding of a partial autopsy case. Thrombocytopenic purpura is mostly responsible for episodes of mucocutaneous bleeding. Thrombotic thrombocytopenic purpura ttp is the most extensive and dangerous intravascular platelet clumping disorder. Purpura results from the extravasation of blood cells into the skin andor mucous membranes giving rise to small purple coloured areas that do not disappear under pressure. Trombocitopenia inmune primaria pediatria integral. Approach to the investigation and management of immune thrombocytopenic purpura in children. Purpura trombocitopenica, plaquetas, purpura, autoanticuerpos. Assessment of uk practice for management of acute childhood idiopathic thrombocytopenic purpura against. Purpura trombotica trombocitopenica y sindrome hemolitico.

For more than a halfcentury after its initial recognition, mortality was near 100% and the etiology totally obscure. Hematologia y oncologia pediatricas ha actualizado sus. Esta enfermedad afecta a varones y a mujeres por igual. Purpura trombocitopenica autoinmune caso clinico y revision bibliografica luis angel sequeira rojas s u m m a r y the itp is a blood illness, characterize by thrombocytopenic, and it variability intense level. Immunologic thrombocytopenic purpura itp, bone marrow aspirate. Trombocitopenia inmunitaria primaria alvaradoibarra m 1, aguilarandrade c1, alvarezvera jl, amadorperez ao1, anayacuellar i2, anorvehernandez e3, baezislas pe1, batesmartin ra 1, cervantessanchez i 1, choquecondori di, cortessanchez e, garcia camacho as1, garciafernandez l4, gomezrosas p1, grimaldogomez fa5. Purpura are injuries caused by the extravasation of blood cells into the skin and or mucous membranes due to hemostasis disorders. The etiopathogenic mechanisms may result from abnormalities in any of the three components of hemostasis. It can produced in health people, but in children has been associated to viral infection, or bacterial infection. He proposed that a powerful poison with both agglutina. Protocolo clinico e diretrizes terapeuticas purpura.

Chronic immune thrombocytopenic purpura itp is a bleeding disorder characterized by increased destruction of platelets due to the production of antiplatelet autoantibodies. Protocolo clinico e diretrizes terapeuticas portaria sasms n. Purpura trombocitopenica autoinmune caso clinico y. Thrombotic thrombocitopenic purpura is a rare disease with a morphological expression featured of many microthrombi in the terminal arterioles of several vital structures.